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| Author: F CUNIN,TA SCHMEDAKE, JR LINK,YY LI, J KOH, SN BHATIA, MJ SAILOR (Fellow) |
Reads: 1202
Pages Viewed: 1216
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Domain:
Medicine; Category:
Equipment; Subcategory: Biometrics
Upload Date: 21st-Apr-2008 Click On Above Link To See More |
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| Short URL: http://medical.wesrch.com/pdfME14GW41VARSS |
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| Comments below ordered by Most Recent First |
WeSRCH's Best of the Internet Award
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Comment : Summary: Strategies to encode or label small particles or beads
for use in screening and bioassay applications focus on spatially
differentiated, on-chip arrays or random distributions of encoded
beads. Attempts to encode large numbers of polymeric, metallic or
glass beads in random arrays or in fluid suspension have used a
variety of entities to provide coded elements (bits)—fluorescent
molecules, molecules with specific vibrational signatures,quantum
dots, or discrete metallic layers. . . .
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WeSRCH's Best of the Internet Award
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Comment : . . . Here we report a method for optically encoding
micrometre-sized nanostructured particles of porous silicon. We
generate multilayered porous films in crystalline silicon using a
periodic electrochemical etch. . . .
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WeSRCH's Best of the Internet Award
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Comment : This results in photonic crystals with well-resolved and narrow
optical reflectivity features,whose wavelengths are determined by
the etching parameters11.Millions of possible codes can be
prepared this way. Micrometre-sized particles are then produced
by ultrasonic fracture, mechanical grinding or by lithographic
means. A simple antibody-based bioassay using fluorescently
tagged proteins demonstrates the encoding strategy in
biologically relevant media.
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