Medical Home»RAAS Hormones, Cardio-Vasular Remodeling, and Aldosterone Antagonists, Medicine, Page 81

RAAS Hormones, Cardio-Vasular Remodeling, and Aldosterone Antagonists, Medicine, Page 81

RAAS Hormones, Cardio-Vasular Remodeling, and Aldosterone Antagonists

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Increased cardiovascular events in patients
with primary aldosteronism


Primary Essential p
Aldosteronism Hypertension
(n = 124) (n = 465)

Age (years) 52 ± 10 52 ± 10 NS
Male/Female (%) 67 / 33 63 / 37 NS

SBP (mmHg) 176 ± 23 174 ± 20 NS
DBP (mmHg) 107 ± 14 106 ± 14 NS

Serum potassium (mmol/l) 3.5 ± 0.3 4.4 ± 0.3 0.0001
Active plasma renin (pg/ml) 4.7 ± 2.6 17.5 ± 15.3 0.0001
Serum aldosterone (pg/ml) 374 ± 174 116 ± 60 0.0001
Urinary aldosterone (µg/24h) 34 ± 17 16 ± 6 0.01



(Milliez et al. JACC 1998)

 

 
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