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RAAS Hormones, Cardio-Vasular Remodeling, and Aldosterone Antagonists, Medicine, Page 16

RAAS Hormones, Cardio-Vasular Remodeling, and Aldosterone Antagonists

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Effect of triple therapy with an ACE inhibitor, beta-
blocker and aldosterone antagonist.

0: Placebo

1: ACEI
0
1 2: ACEI + BB

0 1 2 3: ACEI + BB + AA
2 3 3
4
4: Total lives saved
4 over 2 years



Update of clinical trials from the Am. College of Cardiology 2003.
Based on SOLVD, MERIT and EPHESUS (for NYHA II)
and CONSENSUS, COPERNICUS and RALES (for NYHA III/IV).

(Cleland JGF, et al. Eur J Heart Fail. 2003)

 
 
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