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Optimal Antibiotics Administration, Medicine, Page 16

Optimal Antibiotics Administration

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See entire paper: http://medical.wesrch.com/pdfME1XXF2B2KLBD
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Optimal Antibiotics Administration
Hydrophilic Lipophilic
agents agents

Smaller volume of Larger volume of
distribution distribution
Likely to be renally Likely to be hepatically
eliminated unchanged metabolized
Increased clearance in More likely to penetrate
severe sepsis deep tissues


Fluoroquinolones
Beta lactams
Macrolides
Aminoglycosides
Rifampicin
Glycopeptides
Linezolid

 
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