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Semiconductor Biosensing Technology, Medicine, Page 37

Semiconductor Biosensing Technology

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See entire paper: http://medical.wesrch.com/pdfME14GWGS4HYXR
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Immobilization of oligonucleotide probe
Silanization of Si3N4 insulated gate surface



Glutaraldehyde



3-Aminopropyltriethoxysilane Sodium Cyanoborohyderide
Si/SiO2/Si3N4 Si/SiO2/Si3N4

Reaction between amino-group
and aldehyde-group




Sodium Cyanoborohyderide Si/SiO2/Si3N4
Si/SiO2/Si3N4

Immobilization of amino-group labeled Block of free aldehyde surface
oligonucleotide with glycine


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