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Semiconductor Biosensing Technology, Medicine, Page 30

Semiconductor Biosensing Technology

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hOATP-C transporter

◎Organic Anion Transporting Peptide-C (OATP-C)
→ヒト肝臓で特異的なトランスポーター Wild type Mutant
type


SNPs頻度
name Frequency (%)

Europe African Saharan Chinese Japanese
American African
Reference
(NM_006446) *1a


N130D A:0.61,G:0.39 A:0.28,G:0.72 A:0.19,G:0.81 A:0.20,G:0.80 A:0.36,G:0.64
(A388G) *1b (n=114) (n=23) (n=90) (n=69) (n=44)

V174A T:0.92,C:0.08 Africa Asia
(T521C) *5
(n=24) T:0.98,C:0.02 (n=23) T:0.88,C:0.12 (n=24)

N130D
/V174A *15




次世代チップ 2010/10/28